SCH 206272 is a selective antagonist of tachykinin (NK) receptors, effectively inhibiting binding at human NK(1), NK(2), and NK(3) receptors with Ki values of 1.3, 0.4, and 0.3 nM, respectively. This compound demonstrates significant biological activity in modulating neurokinin signaling pathways, making it valuable in research applications related to pain, anxiety, and other tachykinin-related disorders. Additionally, SCH 206272 is orally active, facilitating its use in in vivo studies.
SCH 206272 is a selective antagonist of tachykinin (NK) receptors, effectively inhibiting binding at human NK(1), NK(2), and NK(3) receptors with Ki values of 1.3, 0.4, and 0.3 nM, respectively. This compound demonstrates significant biological activity in modulating neurokinin signaling pathways, making it valuable in research applications related to pain, anxiety, and other tachykinin-related disorders. Additionally, SCH 206272 is orally active, facilitating its use in in vivo studies.
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