SCH-39370 is a highly selective inhibitor of neutral metalloendopeptidase (NEP), exhibiting an IC50 value of 11.2 nM in rabbit kidney assays. This compound enhances the biological responses to atrial natriuretic factor and demonstrates significant antihypertensive effects in desoxycorticosterone acetate-sodium hypertensive rat models. SCH-39370 is valuable for research on cardiovascular function and the regulation of blood pressure through NEP inhibition.
SCH-39370 is a highly selective inhibitor of neutral metalloendopeptidase (NEP), exhibiting an IC50 value of 11.2 nM in rabbit kidney assays. This compound enhances the biological responses to atrial natriuretic factor and demonstrates significant antihypertensive effects in desoxycorticosterone acetate-sodium hypertensive rat models. SCH-39370 is valuable for research on cardiovascular function and the regulation of blood pressure through NEP inhibition.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
