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SCH 430765

Catalog No.: A62266
NPY5 Receptor Antagonist
SCH 430765 is a potent and selective antagonist of the neuropeptide Y5 (NPY5) receptor. This compound plays a significant role in modulating appetite and energy homeostasis, making it valuable for research into obesity and related metabolic disorders. Its ability to inhibit NPY5 receptor activity provides insights into potential therapeutic strategies for weight management and obesity-related conditions.
SCH 430765 405057-30-9 NPY5 Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSCH 430765 is a potent and selective antagonist of the neuropeptide Y5 (NPY5) receptor. This compound plays a significant role in modulating appetite and energy homeostasis, making it valuable for research into obesity and related metabolic disorders. Its ability to inhibit NPY5 receptor activity provides insights into potential therapeutic strategies for weight management and obesity-related conditions.
Product Information
Catalog NumA62266
FormulaC20H24FN3O3S
Molecular Weight405.49
CAS Number405057-30-9
SMILESO=C(N(C)C1CCN(S(C)(=O)=O)CC1)NC(C=C2)=CC=C2C3=CC(F)=CC=C3
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GPCR/G Protein > NPY receptor