Scyliorhinin I is a potent agonist of the tachykinin receptors NK-1 and NK-2, exhibiting Ki values of 0.9 nM and 2 nM, respectively, for rat submandibular gland NK-1 and hamster bladder NK-2 receptors. This compound is known to induce contraction of the longitudinal muscles in the guinea pig ileum, making it a valuable tool for studying gastrointestinal motility and tachykinin receptor signaling. It is relevant in research focusing on neurogenic inflammation and enteric neuron activity.
Scyliorhinin I is a potent agonist of the tachykinin receptors NK-1 and NK-2, exhibiting Ki values of 0.9 nM and 2 nM, respectively, for rat submandibular gland NK-1 and hamster bladder NK-2 receptors. This compound is known to induce contraction of the longitudinal muscles in the guinea pig ileum, making it a valuable tool for studying gastrointestinal motility and tachykinin receptor signaling. It is relevant in research focusing on neurogenic inflammation and enteric neuron activity.
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