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Scyliorhinin I

Tachykinin Receptor Agonist

Scyliorhinin I is a potent agonist of the tachykinin receptors NK-1 and NK-2, exhibiting Ki values of 0.9 nM and 2 nM, respectively, for rat submandibular gland NK-1 and hamster bladder NK-2 receptors. This compound is known to induce contraction of the longitudinal muscles in the guinea pig ileum, making it a valuable tool for studying gastrointestinal motility and tachykinin receptor signaling. It is relevant in research focusing on neurogenic inflammation and enteric neuron activity.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	103425-21-4
Applications	Tachykinin Receptor Agonist
Formula	C₅₉H₈₇N₁₃O₁₃S
Molecular Weight	1218.47
SMILES	OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCSC)=O)=O)=O)NC([C@@H](NC([C@H](CCCCN)NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](NC([C@@H](N)C)=O)CCCCN)=O)CC2=CC=CC=C2)=O)=O)=O)CC3=CC=CC=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.