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Scyliorhinin II

Catalog No.: A62057
Neurokinin Receptor Agonist
Scyliorhinin II is a selective neurokinin-3 receptor agonist, exhibiting a Ki value of 2.5 nM for the neurokinin-3 receptor in rat cerebral cortex. This compound plays a significant role in modulating neurogenic inflammatory processes and has potential applications in the study of neurokinin signaling pathways. It is valuable for researching the physiological and pharmacological roles of neurokinin receptors in various biological systems.
Scyliorhinin II 112748-19-3 Neurokinin Receptor Agonist
Grouped product items
Size Price Stock Qty
1mg
$80.00
In stock
5mg
$175.00
In stock
10mg
$290.00
In stock
25mg
$580.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionScyliorhinin II is a selective neurokinin-3 receptor agonist, exhibiting a Ki value of 2.5 nM for the neurokinin-3 receptor in rat cerebral cortex. This compound plays a significant role in modulating neurogenic inflammatory processes and has potential applications in the study of neurokinin signaling pathways. It is valuable for researching the physiological and pharmacological roles of neurokinin receptors in various biological systems.
Product Information
Catalog NumA62057
FormulaC77H119N21O26S3
Molecular Weight1851.09
CAS Number112748-19-3
SequenceSer-Pro-Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2
Sequence shorteningSPSNSKCPDGPDCFVGLM-NH2
SMILESO=C1N2[C@@](CCC2)(C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N3[C@](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)C(C)C)=O)=O)CSSC[C@@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]5N(C([C@H](CO)N)=O)CCC5)CO)=O)CC(N)=O)=O)CO)=O)CCCCN)=O)(CCC3)[H])[H]
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GPCR/G Protein > Neurokinin Receptors