Fig. 1 · Structure
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SD-2590 hydrochloride
MMP Inhibitor
SD-2590 hydrochloride is a highly potent inhibitor of matrix metalloproteinases (MMPs), exhibiting IC50 values of less than 0.1 nM for MMP2 and MMP13, 0.18 nM for MMP9, and 1.7 nM for MMP8. This compound effectively inhibits the dilation of the left ventricle in rat models, demonstrating its potential for cardiovascular research applications. The selective inhibition of MMPs by SD-2590 can provide valuable insights into various pathological processes, including tissue remodeling and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 226395-93-3 |
| Applications | MMP Inhibitor |
| Formula | C22H26ClF3N2O7S |
| Molecular Weight | 554.96 |
| SMILES | O=S(C1(CCN(CCOC)CC1)C(NO)=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.