Fig. 1 · Structure
Documents & Downloads
SD-7300
MMPs Inhibitor
SD-7300 is a potent and selective inhibitor of matrix metalloproteinases (MMP-2, MMP-9, and MMP-13) with Ki values of 0.03, 0.01, and 0.03 nM, respectively. This compound effectively reduces extracellular matrix degradation by tumor cells, thus inhibiting their invasion and metastasis. Additionally, SD-7300 serves as a dose-dependent inhibitor of corneal angiogenesis in mice and mitigates interleukin-1-induced cartilage degradation in bovine models. It is valuable for research applications focused on breast cancer and related studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 748120-89-0 |
| Applications | MMPs Inhibitor |
| Formula | C21H30F3N3O7S |
| Molecular Weight | 525.54 |
| Synonyms | SC-81490; PF-02881307 |
| SMILES | O=C(C1(S(=O)(N2CCC(CC2)OC3=CC=C(C=C3)OC(F)(F)F)=O)CCN(CC1)CCOC)NO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.