Fig. 1 · Structure

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SDH-IN-43

SDH Inhibitor

SDH-IN-43 is a potent inhibitor of succinate dehydrogenase (SDH). It exhibits significant inhibitory activity in Caenorhabditis elegans, with an IC50 value of 6.67 μM, leading to marked reductions in reproductive and movement abilities. This compound is also effective against drug-resistant strains of various anthelmintics, making it a valuable tool for research on parasitic infections.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 163105-64-4
Applications SDH Inhibitor
Formula C14H10ClN
Molecular Weight 227.69
SMILES
ClC1=CC=C(C2=CC=C3NC=CC3=C2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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