SDZ NKT 343

Catalog No.: A62022
NK1 Receptor Antagonist
SDZ NKT 343 is a selective NK1 receptor antagonist, exhibiting an IC50 of 0.62 nM against the human NK1 receptor. This compound demonstrates significant analgesic activity, making it valuable for research focused on pain management and neuropharmacology. SDZ NKT 343 can be utilized in studies investigating the role of NK1 receptors in various physiological and pathological processes.
Grouped product items
Size Price Stock Qty
5mg
$340.00
In stock
10mg
$555.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSDZ NKT 343 is a selective NK1 receptor antagonist, exhibiting an IC50 of 0.62 nM against the human NK1 receptor. This compound demonstrates significant analgesic activity, making it valuable for research focused on pain management and neuropharmacology. SDZ NKT 343 can be utilized in studies investigating the role of NK1 receptors in various physiological and pathological processes.
Product Information
Catalog NumA62022
FormulaC33H33N5O5
Molecular Weight579.65
CAS Number180046-99-5
SMILESO=C(NC([C@H]1N(C(NC2=CC=CC=C2[N+]([O-])=O)=O)CCC1)=O)[C@H](CC3=CC=C4C=CC=CC4=C3)N(C)CC5=CC=CC=C5
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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