Fig. 1 · Structure
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SDZ NKT 343
NK1 Receptor Antagonist
SDZ NKT 343 is a selective NK1 receptor antagonist, exhibiting an IC50 of 0.62 nM against the human NK1 receptor. This compound demonstrates significant analgesic activity, making it valuable for research focused on pain management and neuropharmacology. SDZ NKT 343 can be utilized in studies investigating the role of NK1 receptors in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 180046-99-5 |
| Applications | NK1 Receptor Antagonist |
| Formula | C33H33N5O5 |
| Molecular Weight | 579.65 |
| SMILES | O=C(NC([C@H]1N(C(NC2=CC=CC=C2[N+]([O-])=O)=O)CCC1)=O)[C@H](CC3=CC=C4C=CC=CC4=C3)N(C)CC5=CC=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.