Secalonic acid D is a potent apoptosis inducer that targets GSK3-β, leading to the degradation of β-catenin. Isolated from the metabolites of Aspergillus aculeatus, this compound effectively down-regulates c-Myc expression and induces cell cycle arrest at the G1 phase. Its mechanism of action makes Secalonic acid D valuable for research on tumor cell apoptosis and cell cycle regulation in cancer studies.
Secalonic acid D is a potent apoptosis inducer that targets GSK3-β, leading to the degradation of β-catenin. Isolated from the metabolites of Aspergillus aculeatus, this compound effectively down-regulates c-Myc expression and induces cell cycle arrest at the G1 phase. Its mechanism of action makes Secalonic acid D valuable for research on tumor cell apoptosis and cell cycle regulation in cancer studies.
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