Selegiline-d5 hydrochloride is a deuterium-labeled form of the irreversible monoamine oxidase B (MAO-B) inhibitor, Selegiline. This compound exhibits a high selectivity for MAO-B with an IC50 of 51 nM, demonstrating 450-fold preference over MAO-A (IC50 = 23 μM). Selegiline-d5 hydrochloride is utilized in research related to neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, and major depressive disorder, providing valuable insights into the biochemical pathways involved in these conditions.
Selegiline-d5 hydrochloride is a deuterium-labeled form of the irreversible monoamine oxidase B (MAO-B) inhibitor, Selegiline. This compound exhibits a high selectivity for MAO-B with an IC50 of 51 nM, demonstrating 450-fold preference over MAO-A (IC50 = 23 μM). Selegiline-d5 hydrochloride is utilized in research related to neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, and major depressive disorder, providing valuable insights into the biochemical pathways involved in these conditions.
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