Selegiline-d5

Catalog No.: A79117
Stable Isotope
Selegiline-d5 is a deuterium-labeled derivative of Selegiline, targeting the selective and irreversible inhibition of monoamine oxidase B (MAO-B) with an IC50 of 51 nM. This compound demonstrates a 450-fold selectivity for MAO-B over MAO-A (IC50=23 µM). Selegiline-d5 is valuable for research into neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, as well as in the investigation of major depressive disorder.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSelegiline-d5 is a deuterium-labeled derivative of Selegiline, targeting the selective and irreversible inhibition of monoamine oxidase B (MAO-B) with an IC50 of 51 nM. This compound demonstrates a 450-fold selectivity for MAO-B over MAO-A (IC50=23 µM). Selegiline-d5 is valuable for research into neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, as well as in the investigation of major depressive disorder.
Product Information
Catalog NumA79117
FormulaC13H12D5N
Molecular Weight192.31
CAS Number1217976-51-6
SMILESC#CCN(C)[C@H](C)CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]
SynonymsDeprenyl-d5; (-)-Selegiline-d5; (-)-Deprenyl-d5
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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