Selegiline-d5 is a deuterium-labeled derivative of Selegiline, targeting the selective and irreversible inhibition of monoamine oxidase B (MAO-B) with an IC50 of 51 nM. This compound demonstrates a 450-fold selectivity for MAO-B over MAO-A (IC50=23 µM). Selegiline-d5 is valuable for research into neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, as well as in the investigation of major depressive disorder.
Selegiline-d5 is a deuterium-labeled derivative of Selegiline, targeting the selective and irreversible inhibition of monoamine oxidase B (MAO-B) with an IC50 of 51 nM. This compound demonstrates a 450-fold selectivity for MAO-B over MAO-A (IC50=23 µM). Selegiline-d5 is valuable for research into neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, as well as in the investigation of major depressive disorder.
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