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Selnoflast monopotassium

NLRP3 Inhibitor

Selnoflast monopotassium is a selective and reversible small molecule inhibitor targeting the NLRP3 inflammasome. It effectively inhibits IL-1β release induced by NLRP3 activation in monocyte-derived macrophages from individuals with Alzheimer's disease. This compound shows significant promise for research applications related to Alzheimer's disease and other systemic inflammatory disorders, including ulcerative colitis and chronic obstructive pulmonary disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2260969-37-5
Applications	NLRP3 Inhibitor
Formula	C₂₀H₂₈KN₃O₃S
Molecular Weight	429.62
Synonyms	Somalix monopotassium; RO-7486967 monopotassium; IZD334 monopotassium
SMILES	O=C([N-]S(=O)(C1CCN(CC)CC1)=O)NC2=C(CCC3)C3=CC4=C2CCC4.[K+]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.