Catalog No.: A21582

Neurokinin-1 (NK-1) receptor antagonist


Serlopitant Chemical Structure

CAS NO. 860642-69-9

Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.

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Biological Activity

Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18 mL 90 mL 180.01 mL
0.5 mM 3.6 mL 18 mL 36 mL
1 mM 1.8 mL 9 mL 18 mL
5 mM 0.36 mL 1.8 mL 3.6 mL

*The above data is based on the productmolecular weight 555.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21582
Actions Antagonist
CAS No. 860642-69-9
Formula C29H28F7NO2
M. Wt 555.53
Purity >98%
Synonyms VPD-737, VPD737, VPD 737; MK-0594, MK0594, MK 0594
SMILES O=C1C=C(N2C[[email protected]@]3([H])CC[[email protected]](O[[email protected]@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)[[email protected]@H](C5=CC=C(F)C=C5)[[email protected]]3([H])C2)CC1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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