Fig. 1 · Structure

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SerSA

Chemical probes

SerSA is a selective inhibitor of seryl-tRNA synthetases, effectively targeting EcSerRS, SaSerRS, and HsSerRS with IC50 values of 0.21, 0.23, and 2.17 μM, respectively. This compound serves as a valuable chemical probe for investigating the role of seryl-tRNA synthetases in cellular processes. Its ability to modulate aminoacyl-tRNA synthesis highlights its potential in pharmaceutical research and studies on translation-related pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 299437-44-8
Applications Chemical probes
Formula C13H19N7O8S
Molecular Weight 433.40
SMILES
O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1COS(NC([C@@H](N)CO)=O)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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