Fig. 1 · Structure
Documents & Downloads
Seviteronel (R enantiomer)
Cat. No.
A69750
CAS
1375603-38-5
CYP17 Lyase Inhibitor
Seviteronel (R enantiomer) is a potent inhibitor of CYP17 lyase, with an h-Lyase IC50 value of 69 nM. This compound specifically targets the cytochrome P450 17A1 enzyme, crucial in steroidogenesis, and has applications in research focused on hormone-dependent cancers. Its efficacy in inhibiting steroid biosynthesis makes it a valuable reagent for studies investigating hormonal modulation and therapeutic interventions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1375603-38-5 |
| Applications | CYP17 Lyase Inhibitor |
| Formula | C18H17F4N3O3 |
| Molecular Weight | 399.34 |
| Synonyms | VT-464 (R enantiomer) |
| SMILES | FC(F)OC1=C(OC(F)F)C=C(C=CC([C@@](C2=CNN=N2)(C(C)C)O)=C3)C3=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.