Fig. 1 · Structure
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SG3199-Val-Ala-PAB
Tesirine Intermediate
SG3199-Val-Ala-PAB is an intermediate in the synthesis of Tesirine, an antibody-drug conjugate (ADC) designed for targeted cancer therapy. Tesirine functions by delivering cytotoxic agents directly to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects. This compound is essential for research applications focused on developing ADCs for various cancer treatments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1595275-61-8 |
| Applications | Tesirine Intermediate |
| Formula | C49H59N7O11 |
| Molecular Weight | 922.03 |
| SMILES | O=C(NC1=CC=C(COC(N2[C@@H](O)[C@@](CC(C)=C3)([H])N3C(C4=CC(OC)=C(OCCCCCOC5=C(OC)C=C6C(N7[C@](CC(C)=C7)([H])C=NC6=C5)=O)C=C42)=O)=O)C=C1)[C@H](C)NC([C@H](C(C)C)N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.