sGC activator 1

Catalog No.: A60884
sGC Activator
sGC activator 1 is a potent activator of soluble guanylate cyclase (sGC), a key enzyme involved in the nitric oxide signaling pathway. By enhancing sGC activity, this compound increases intracellular levels of cyclic guanosine monophosphate (cGMP), leading to various biological effects such as vasodilation and smooth muscle relaxation. sGC activator 1 is utilized in research applications focused on cardiovascular diseases, neuroprotection, and cellular signaling mechanisms.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionsGC activator 1 is a potent activator of soluble guanylate cyclase (sGC), a key enzyme involved in the nitric oxide signaling pathway. By enhancing sGC activity, this compound increases intracellular levels of cyclic guanosine monophosphate (cGMP), leading to various biological effects such as vasodilation and smooth muscle relaxation. sGC activator 1 is utilized in research applications focused on cardiovascular diseases, neuroprotection, and cellular signaling mechanisms.
Product Information
Catalog NumA60884
FormulaC27H22ClF5N6O3
Molecular Weight608.95
CAS Number2101645-33-2
SMILESC[C@]1(C2=CC=C(C=C2)CCC(O)=O)C3=C(N)N=C(C4=NN(CCC(F)(F)C(F)(F)F)C5=CC(Cl)=CC=C45)N=C3NC1=O
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