Fig. 1 · Structure
Documents & Downloads
SGC agonist 2
SGC Agonist
SGC Agonist 2 is a selective agonist of soluble guanylate cyclase (SGC), an essential enzyme in the nitric oxide (NO) signaling pathway that produces cyclic GMP (cGMP). This compound demonstrates significant biological activity in modulating vasodilation and has implications for research into cardiovascular diseases, including heart failure, pulmonary hypertension, angina, and myocardial infarction, as well as fibrotic conditions such as renal fibrosis and systemic sclerosis. Its utility in investigating these pathologies makes SGC Agonist 2 a valuable tool for advancing cardiovascular and fibrosis-related research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2735713-77-4 |
| Applications | SGC Agonist |
| Formula | C23H17F2N7O2 |
| Molecular Weight | 461.42 |
| SMILES | O=C1[C@]2([H])C3=C(N1)NC(C(C4=C5)=NN(CC6=C(C=CC=C6)F)C4=NC=C5F)=NC3=NC(C2(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.