SGC8158

Name: SGC8158
Brand: Adooq Bioscience
SKU: A24395
Rating: 5 (288 reviews)

Catalog No.: A24395

PRMT7 inhibitor

SGC8158 is a potent inhibitor of PRMT7, useful for investigating PRMT7's cellular functions. It reduces monomethylarginine levels on Hsp70, a key PRMT7 substrate. SGC8158 exhibits growth inhibitory effects in various cancer cells, including multidrug-resistant (MDR) cancer cells, with IC50 values ranging from 2 to 9 μM.

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Grouped product items
Size	Price	Stock
1mg	$135.00	In stock
5mg	$405.00	In stock
10mg	$690.00	In stock
50mg	$2,070.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description	SGC8158 is a potent inhibitor of PRMT7, useful for investigating PRMT7's cellular functions. It reduces monomethylarginine levels on Hsp70, a key PRMT7 substrate. SGC8158 exhibits growth inhibitory effects in various cancer cells, including multidrug-resistant (MDR) cancer cells, with IC50 values ranging from 2 to 9 μM.

Product Information

Catalog Num	A24395
Formula	C27H31ClN6O3S
Molecular Weight	555.09
CAS Number	3062376-84-2
SMILES	O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1CSCCCCNCC4=CC=CC(C5=CC=C(Cl)C=C5)=C4
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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