Fig. 1 · Structure
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Sheng Gelieting
DP-IV Inhibitor
Sheng Gelieting (CGT-8012) is a selective dipeptidyl peptidase IV (DP-IV) inhibitor with notable activity, exhibiting an IC50 value of 87 nM. This compound is primarily used in research focused on metabolic diseases, particularly type 2 diabetes, by modulating insulin signaling and glucose homeostasis. Sheng Gelieting is instrumental in studies aimed at elucidating the role of DP-IV in glucose metabolism and the development of related therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1152810-23-5 |
| Applications | DP-IV Inhibitor |
| Formula | C17H16F6N4O |
| Molecular Weight | 406.33 |
| Synonyms | CGT-8012 |
| SMILES | FC(F)(C1=NC=C2N1CCN(C(C[C@H](N)CC3=C(C=C(C(F)=C3)F)F)=O)C2)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.