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SHP2-IN-19

SHP2 Inhibitor

SHP2-IN-19 is a selective SHP2 inhibitor with an IC50 of 3 nM, demonstrating potent inhibitory activity against the SHP2 enzyme. This compound is primarily utilized in the study of glioblastoma, offering valuable insights into the role of SHP2 signaling in cancer progression and therapeutic resistance. Its high potency makes it a useful tool for evaluating SHP2's contribution to various biological processes and potential treatments in oncological research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2941498-84-4
Applications	SHP2 Inhibitor
Formula	C₂₇H₂₈N₆O₂
Molecular Weight	468.55
SMILES	CC1=C(N2C(C(N3CCC4(CC(N=CC=C5)=C5[C@H]4N)CC3)=N1)=CC=N2)C6=CC(OCCO7)=C7C=C6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.