Fig. 1 · Structure

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SHP2-IN-20

SHP2 Inhibitor

SHP2-IN-20 is a selective inhibitor of the protein tyrosine phosphatase SHP2, displaying an IC50 value of 3 nM. This compound is primarily utilized in research focused on glioblastoma, where it aids in the investigation of SHP2's role in oncogenic signaling pathways and potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2941498-94-6
Applications SHP2 Inhibitor
Formula C25H24F2N6
Molecular Weight 446.50
SMILES
FC1=CC(F)=CC=C1C2=C(C)N=C(N3CCC4(CC(N=CC=C5)=C5[C@H]4N)CC3)C6=CC=NN26

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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