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SHP2-IN-34

Anticancer Agent

SHP2-IN-34 is a phenyl urea derivative that acts as a selective inhibitor of the SHP2 enzyme, demonstrating promising anti-cancer activity. In preclinical studies using the CT26 mouse model, SHP2-IN-34 significantly inhibits tumor growth, highlighting its potential for innovative cancer therapies. This reagent is valuable for research applications focused on the mechanistic role of SHP2 in oncogenesis and therapeutic development against various malignancies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2924065-12-1
Applications	Anticancer Agent
Formula	C₂₃H₂₅Cl₂N₇OS
Molecular Weight	518.46
SMILES	O=C(NC1=C(Cl)C(SC2=NC=C(N3CCC(C)(CC3)N)N=C2N)=CC=C1)NC4=CC(Cl)=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.