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SHP2-IN-41

SHP2 Inhibitor

SHP2-IN-41 is a potent inhibitor of the SHP2 protein, exhibiting an IC50 of less than 0.1 μM in biochemical assays. It also demonstrates significant inhibitory activity against KYSE-520 cancer cells with an IC50 of less than 0.1 μM. This compound serves as a valuable tool in cancer research, particularly in studies exploring SHP2's role in oncogenic signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3081261-84-6
Applications	SHP2 Inhibitor
Formula	C₂₄H₂₄BClN₄O₂S
Molecular Weight	478.80
SMILES	N[C@@H]1C2=C(CC13CCN(CC3)C4=NC=C(N=C4)SC5=CC6=C(B(OC6)O)C=C5Cl)C=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.