SHP2-IN-43 is a potent inhibitor of SHP2, demonstrating an IC50 of 98.7 nM. This compound serves as a valuable ligand for targeted protein degradation (PROTAC) applications, facilitating the synthesis of SHP2-D26. Researchers can utilize SHP2-IN-43 to explore the therapeutic potential of modulating SHP2 activity in various biological contexts.
SHP2-IN-43 is a potent inhibitor of SHP2, demonstrating an IC50 of 98.7 nM. This compound serves as a valuable ligand for targeted protein degradation (PROTAC) applications, facilitating the synthesis of SHP2-D26. Researchers can utilize SHP2-IN-43 to explore the therapeutic potential of modulating SHP2 activity in various biological contexts.
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