Fig. 1 · Structure

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SHP2-IN-5

SHP2 Inhibitor

SHP2-IN-5 is a potent inhibitor of SHP2, with an IC50 of 97 nM. SHP2 is a crucial non-receptor protein tyrosine phosphatase that plays a significant role in regulating cell growth and proliferation. This compound has demonstrated potential for application in cancer research and other SHP2-related human diseases, making it a valuable tool for investigating therapeutic strategies targeting SHP2 pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 54755-93-0
Applications SHP2 Inhibitor
Formula C12H8O6
Molecular Weight 248.19
SMILES
OC1=CC=C(C=C(C(O)=O)C=C(O)C2=O)C2=C1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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