Fig. 1 · Structure
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SHP2 inhibitor LY6
SHP2 Inhibitor
SHP2 inhibitor LY6 is a selective inhibitor targeting the SHP2 protein tyrosine phosphatase, exhibiting an IC50 of 9.8 µM. This compound effectively disrupts SHP2-mediated signaling pathways and cell proliferation. It is suitable for research applications investigating SHP2's role in various cellular processes and its implications in cancer and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2296718-09-5 |
| Applications | SHP2 Inhibitor |
| Formula | C30H27Cl2N3O4 |
| Molecular Weight | 564.46 |
| Synonyms | LY6 |
| SMILES | O=C1N(C2=CCCN(CC3=CC(C(/C=C/C4=CC=C(Cl)C=C4Cl)=O)=C(O)C=C3OCC)C2)C5=CC=CC=C5N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.