Fig. 1 · Structure
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SHP504
SHP2 Inhibitor
SHP504 is a selective inhibitor of SHP2 phosphatase, exhibiting an IC50 of 21 μM for SHP2 1–525. This compound is primarily utilized in research to investigate the role of SHP2 in various signaling pathways and cellular processes. Its inhibition capability makes SHP504 a valuable tool in studies focused on cancer, developmental biology, and autoimmune diseases, facilitating the exploration of therapeutic strategies targeting SHP2-related mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2222280-83-1 |
| Applications | SHP2 Inhibitor |
| Formula | C23H15ClN4O4 |
| Molecular Weight | 446.84 |
| SMILES | O=C(O)C1=CC=C(O)C(C2=NN=C(N3CC4=CC=CC=C4Cl)N2C5=C(C=CC=C5)C3=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.