Shz-1, a small cardiogenic molecule, primarily targets cardiac-specific gene expression. It has been shown to induce the expression of key cardiac markers, including sarcomeric tropomyosin in P19CL6 cells and Nkx2.5 in mouse models. Additionally, Shz-1 activates the axolotl TPM4 promoter, driving ectopic expression in C2C12 cells. This compound is valuable for research in cardiac development and regenerative medicine.
Shz-1, a small cardiogenic molecule, primarily targets cardiac-specific gene expression. It has been shown to induce the expression of key cardiac markers, including sarcomeric tropomyosin in P19CL6 cells and Nkx2.5 in mouse models. Additionally, Shz-1 activates the axolotl TPM4 promoter, driving ectopic expression in C2C12 cells. This compound is valuable for research in cardiac development and regenerative medicine.
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