Fig. 1 · Structure
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Sialyl-Lewis X
Ligand For Selectins
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide that serves as a high-affinity ligand for selectins, including E-, P-, and L-selectin. This compound is critical in mediating cell adhesion and plays a pivotal role in the recruitment of neutrophils to inflammatory sites by binding to ELAM-1 and CD62. Research applications include studying inflammation, immune responses, and potential therapeutic targets for inflammatory diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 98603-84-0 |
| Applications | Ligand For Selectins |
| Formula | C31H52N2O23 |
| Molecular Weight | 820.74 |
| Synonyms | sLeX |
| SMILES | OC([C@](O[C@@]([C@@H]1NC(C)=O)([H])[C@H](O)[C@H](O)CO)(C[C@@H]1O)O[C@@H]([C@H]([C@H]2CO)O)[C@H]([C@@H](O2)O[C@@]([C@H](O)CO)([H])[C@]([C@H](C=O)NC(C)=O)([H])O[C@H](O[C@H]3C)[C@H]([C@@H]([C@@H]3O)O)O)O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.