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Biological Activity
Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (??1 R) antagonist with Kis of 3.88 and 1288 nM for ??1 and ??2 receptor, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.6 mL | 133.02 mL | 266.04 mL |
| 0.5 mM | 5.32 mL | 26.6 mL | 53.21 mL |
| 1 mM | 2.66 mL | 13.3 mL | 26.6 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.32 mL |
*The above data is based on the productmolecular weight 375.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18504 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1639220-15-7 |
| Formula | C20H26ClN3O2 |
| M. Wt | 375.89 |
| Purity | >98% |
| SMILES | CC1=NC(C2=CC=C(OC)C=C2)=NC(OCCCN3CCCCC3)=C1Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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