Fig. 1 · Structure
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Sigma-2 Radioligand 2
Sigma Receptor
Sigma-2 Radioligand 2 selectively targets the sigma-2 receptor with a low nanomolar affinity (Ki(σ2) = 2.30 nM) and exhibits significant subtype selectivity (Ki(σ1)/Ki(σ2) > 1500). This compound is essential for research applications involving sigma receptor pharmacology, allowing for in-depth studies of receptor function and potential therapeutic implications in neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2860554-31-8 |
| Applications | Sigma Receptor |
| Formula | C23H28FN3O3 |
| Molecular Weight | 413.49 |
| SMILES | O=C1N(C2=CC=CC=C2N1CCCCN3CC4=C(C3)C=C(OC)C(OC)=C4)CCF |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.