Sigma-LIGAND-1 hydrochloride is a selective ligand for sigma receptors, exhibiting IC50 values of 16 nM and 19 nM at the DTG and PPP sites, respectively. This compound demonstrates a Ki of 4000 nM at the dopamine D2 receptor, indicating its selectivity for sigma binding. It is valuable for research in neuropharmacology, particularly in studies exploring sigma receptor-mediated signaling pathways and their implications in various neurological disorders.
Sigma-LIGAND-1 hydrochloride is a selective ligand for sigma receptors, exhibiting IC50 values of 16 nM and 19 nM at the DTG and PPP sites, respectively. This compound demonstrates a Ki of 4000 nM at the dopamine D2 receptor, indicating its selectivity for sigma binding. It is valuable for research in neuropharmacology, particularly in studies exploring sigma receptor-mediated signaling pathways and their implications in various neurological disorders.
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