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Sigmoidin B

Name: Sigmoidin B
Brand: Adooq Bioscience
SKU: A76485
Availability: OutOfStock

Cat. No. A76485 CAS 87746-47-2

5-Lipoxygenase Inhibitor

Sigmoidin B is a selective inhibitor of 5-lipoxygenase, targeting the leukotriene synthesis pathway. This prenylated flavanone exhibits significant antioxidant activity by effectively scavenging DPPH radicals. Additionally, Sigmoidin B demonstrates antigenotoxic effects, notably inhibiting genotoxicity induced by Aflatoxin B1 with an IC50 of 18.7 μg/mL, and possesses anti-inflammatory properties. Its diverse biological activities make it a valuable reagent for research in inflammation and oxidative stress-related studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	87746-47-2
Applications	5-Lipoxygenase Inhibitor
Formula	C₂₀H₂₀O₆
Molecular Weight	356.37
SMILES	O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(C/C=C(C)\C)=C(C(O)=C3)O)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.