Simepdekinra

Catalog No.: A35863
IL-17A Antagonist
Simepdekinra is an IL-17A antagonist that plays a crucial role in modulating inflammatory responses. It demonstrates significant potential in the research of moderate to severe plaque-type psoriasis by inhibiting the activity of IL-17A, a key cytokine involved in the pathogenesis of this condition. Its application in preclinical studies provides valuable insights into therapeutic strategies targeting autoimmune skin diseases.
Grouped product items
Size Price Stock Qty
1mg
$575.00
In stock
5mg
$1,475.00
In stock
10mg
$2,300.00
In stock
25mg
$4,450.00
In stock
50mg
$6,970.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSimepdekinra is an IL-17A antagonist that plays a crucial role in modulating inflammatory responses. It demonstrates significant potential in the research of moderate to severe plaque-type psoriasis by inhibiting the activity of IL-17A, a key cytokine involved in the pathogenesis of this condition. Its application in preclinical studies provides valuable insights into therapeutic strategies targeting autoimmune skin diseases.
Product Information
Catalog NumA35863
FormulaC35H50FN7O5
Molecular Weight667.81
CAS Number2978700-29-5
SMILESO=C(C1=CC=NN1CC)N[C@H](C(NC2=C(C=C(C=C2)[C@H](C)[C@@H](NC([C@H](C)OC)=O)C(N3C[C@H](N(CC3)C)C)=O)F)=O)C(C4CC4)C5CC5
SynonymsLY4100511; DC-853
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