SIMR3030 is a highly effective inhibitor of the SARS-CoV-2 PLpro enzyme, exhibiting an IC50 value of 0.0399 µg/mL. This compound demonstrates significant antiviral activity, reducing the expression levels of SARS-CoV spike, ORF1b, IFN-α, and IL-6 mRNA. Additionally, SIMR3030 has shown a favorable safety profile in murine models, making it a valuable reagent for research into COVID-19 therapeutics and fundamental coronavirus biology.
SIMR3030 is a highly effective inhibitor of the SARS-CoV-2 PLpro enzyme, exhibiting an IC50 value of 0.0399 µg/mL. This compound demonstrates significant antiviral activity, reducing the expression levels of SARS-CoV spike, ORF1b, IFN-α, and IL-6 mRNA. Additionally, SIMR3030 has shown a favorable safety profile in murine models, making it a valuable reagent for research into COVID-19 therapeutics and fundamental coronavirus biology.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
