Fig. 1 · Structure

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Sirpiglenastat

Glutamine Antagonist

Sirpiglenastat is a broad-spectrum glutamine antagonist that disrupts tumor metabolism. By targeting glutamine utilization, Sirpiglenastat exhibits significant anticancer effects while simultaneously enhancing the antitumor immune response. This compound is valuable for researchers investigating metabolic pathways in cancer and immune modulation.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2079939-05-0
Applications Glutamine Antagonist
Formula C22H27N5O5
Molecular Weight 441.48
Synonyms DRP-104
SMILES
CC(C)OC([C@H](CCC(C=[N+]=[N-])=O)NC([C@@H](NC(C)=O)CC1=CNC2=CC=CC=C12)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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