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SIS3

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Smad3 inhibitor

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Catalog No. A16065

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
SIS3 5mg A16065-5

Regular Price: $100.00

Special Price: $90.00

SIS3 10mg A16065-10

Regular Price: $180.00

Special Price: $162.00

SIS3 25mg A16065-25

Regular Price: $313.00

Special Price: $281.70

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

SIS3 is a novel specific inhibitor of Smad3. It has effect on transforming growth factor-beta1-induced extracellular matrix expression.

SIS3

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Chemical Information

Catalog Num A16065
Actions Inhibitor
M. Wt 489.99
Formula C28H27N3O3.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 521984-48-5
Synonyms SIS 3
SMILES CN1C(C2=CC=CC=C2)=C(C3=C1N=CC=C3)/C([H])=C([H])/C(N4CCC5=CC(OC)=C(OC)C=C5C4)=O.Cl

Biological Activity

Description
SIS3 is a novel specific inhibitor of Smad3. It has effect on transforming growth factor-beta1-induced extracellular matrix expression.
Targets
Smad3

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.41 mL 102.04 mL 204.09mL
0.5 mM 4.08 mL 20.41 mL 40.82 mL
1 mM 2.04 mL 10.2 mL 20.41 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 489.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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