Sitafloxacin

Catalog No.: A10847

Sitafloxacin

Sitafloxacin Chemical Structure

CAS NO. 127254-12-0

Sitafloxacin is a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. Sitafloxacin is active against methicillin-resistant staphylococci, Streptococcus pneumoniae and other streptococci with reduced susceptibility to levofloxacin and other quinolones and enterococci.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $120.00

Special Price $96.00

25 mg

Regular Price: $200.00

Special Price $160.00

100 mg

Regular Price: $600.00

Special Price $480.00

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Biological Activity

Sitafloxacin is a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. Sitafloxacin is active against methicillin-resistant staphylococci, Streptococcus pneumoniae and other streptococci with reduced susceptibility to levofloxacin and other quinolones and enterococci.
In vitro DMSO Warmed: 4 mg/mL (9.15 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.4 mL 122.01 mL 244.01 mL
0.5 mM 4.88 mL 24.4 mL 48.8 mL
1 mM 2.44 mL 12.2 mL 24.4 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.8178. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10847
CAS No. 127254-12-0
Formula C19H18ClF2N3O3?
M. Wt 409.8178
Purity >98%
Synonyms DU 6859, DU-6859, DU6859, DU 6859A, DU-6859A, DU6859A
SMILES O=C(C1=CN([[email protected]]2[[email protected]@H](F)C2)C3=C(C=C(F)C(N(C[[email protected]]4N)CC54CC5)=C3Cl)C1=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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