SJB3-019A is a potent and novel usp1 inhibitor. SJB3-019A (IC50 = 0.0781 uM) was 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells.
SJB3-019A is a potent and novel usp1 inhibitor. SJB3-019A (IC50 = 0.0781 uM) was 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells.
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A12822
Formula
C16H8N2O3
Molecular Weight
276.25
CAS Number
2070015-29-9
SMILES
O=C(C1=C2OC(C3=CN=CC=C3)=N1)C4=CC=CC=C4C2=O
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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