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SJG-136 intermediate-2

Intermediate

SJG-136 intermediate-2 serves as a crucial intermediate in the synthesis of SJG-136, a potent DNA cross-linking agent. SJG-136 demonstrates significant biological activity with an XL50 value of 45 nM for pBR322 DNA, making it a valuable tool for research in DNA damage and replication studies. This compound is essential for investigations into the mechanisms of action of DNA-targeting therapies and in the development of novel anticancer agents.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2246368-23-8
Applications	Intermediate
Formula	C₂₄H₃₆N₂O₆Si
Molecular Weight	476.64
SMILES	O=C(N1[C@@H](CC(C1)=C)CO[Si](C)(C)C(C)(C)C)C2=C(C=C(C(OC)=C2)O)NC(OCC=C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.