SKF 89748

Catalog No.: A58514
Adrenergic Receptor Agonist
SKF 89748 is an α1-adrenergic receptor agonist known for its role in modulating appetite regulation by inhibiting food and water intake. In studies conducted on adult male rats, SKF 89748 demonstrated an effective dose (ED50) of 0.37 mg/kg for suppressing food consumption. This compound has applications in research focused on feeding behavior, adrenergic signaling pathways, and potential therapeutic strategies for appetite regulation.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSKF 89748 is an α1-adrenergic receptor agonist known for its role in modulating appetite regulation by inhibiting food and water intake. In studies conducted on adult male rats, SKF 89748 demonstrated an effective dose (ED50) of 0.37 mg/kg for suppressing food consumption. This compound has applications in research focused on feeding behavior, adrenergic signaling pathways, and potential therapeutic strategies for appetite regulation.
Product Information
Catalog NumA58514
FormulaC12H17NOS
Molecular Weight223.33
CAS Number81998-18-7
SMILESNC1CC2=C(CC1)C(SC)=CC=C2OC
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