SKL2001

Catalog No.: A16707

Wnt/β-catenin agonist

SKL2001

SKL2001 Chemical Structure

CAS NO. 909089-13-0

SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.

Availability: In stock

Package Price Qty
10 mg
$63.00
25 mg
$126.00
50 mg
$217.00
100 mg
$371.00
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Biological Activity

SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.
In vitro (25°C) DMSO 50 mg/mL (174.64 mM)
Water Insoluble
Ethanol 50 mg/mL (174.64 mM)
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.93 mL 174.65 mL 349.3 mL
0.5 mM 6.99 mL 34.93 mL 69.86 mL
1 mM 3.49 mL 17.46 mL 34.93 mL
5 mM 0.7 mL 3.49 mL 6.99 mL

*The above data is based on the productmolecular weight 286.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16707
Actions Agonist
CAS No. 909089-13-0
Formula C14H14N4O3
M. Wt 286.29
Purity >98%
Synonyms SKL 2001, SKL-2001
SMILES O=C(C1=NOC(C2=CC=CO2)=C1)NCCCN3C=CN=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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