Biological Activity
SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.93 mL | 174.65 mL | 349.3 mL |
0.5 mM | 6.99 mL | 34.93 mL | 69.86 mL |
1 mM | 3.49 mL | 17.46 mL | 34.93 mL |
5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
*The above data is based on the productmolecular weight 286.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16707 |
---|---|
Actions | Agonist |
M. Wt | 286.29 |
Formula | C14H14N4O3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 909089-13-0 |
Synonyms | SKL 2001, SKL-2001 |
SMILES | O=C(C1=NOC(C2=CC=CO2)=C1)NCCCN3C=CN=C3 |
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