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SL-052

Photosensitizer

SL-052 is a hypocrellin-based photosensitizer primarily targeting cancer cells through photodynamic therapy (PDT). Encapsulated within biodegradable polylactic-co-glycolic acid (PLGA) nanoparticles, this formulation demonstrates enhanced effectiveness in treating subcutaneous SCCVII squamous cell carcinoma. Optimized via single emulsion solvent evaporation technology, SL-052-PLGA nanoparticles exhibit superior therapeutic outcomes compared to other SL-052 formulations. Prolonging the interval between drug administration and tumor illumination further augments tumor cure rates, establishing SL-052-PLGA as a promising candidate for cancer PDT applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	925438-34-2
Applications	Photosensitizer
Formula	C₃₅H₃₂N₂O₇
Molecular Weight	592.64
SMILES	COC(C([C@H](C(C)=CC1=C(N[C@](CCCC2)([H])[C@@]2([H])N3)C3=C4C5=O)C(C)=O)=C6C1=C4C(C(OC)=C5)=C7C6=C8C(C=C7OC)=O)=C8O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.