Fig. 1 · Structure

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SLC26A3-IN-1

SLC26A3 Inhibitor

SLC26A3-IN-1 is a selective inhibitor of the anion exchanger SLC26A3, with an IC50 value of 340 nM. Primarily implicated in the intestinal absorption of chloride and oxalate, SLC26A3 plays a crucial role in maintaining ion homeostasis. This compound is valuable for research on chloride-losing diarrhea and related disorders, as mutations that impair SLC26A3 function have been associated with this condition. Use of SLC26A3-IN-1 can enhance investigations into therapeutic strategies targeting SLC26A3 in various gastrointestinal diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 307552-53-0
Applications SLC26A3 Inhibitor
Formula C23H18O4
Molecular Weight 358.39
SMILES
O=C(C1=C(C2=CC=CC=C2)OC3=C1C=C(OCC4=C(C)C=CC=C4)C=C3)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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