Fig. 1 · Structure
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SLC26A3-IN-2
SLC26A3 Inhibitor
SLC26A3-IN-2 is a selective inhibitor of the anion exchanger SLC26A3, demonstrating an IC50 of 360 nM. This compound is essential for investigating the role of SLC26A3 in intestinal absorption processes, specifically in the transport of chloride and oxalate. The modulation of SLC26A3 activity is relevant for studying disorders associated with its dysfunction, such as chloride-losing diarrhea and adenoma pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 950348-60-4 |
| Applications | SLC26A3 Inhibitor |
| Formula | C19H13ClN2O2S |
| Molecular Weight | 368.84 |
| SMILES | O=C1C=C(N=C2SC=C(N12)C3=CC=CC=C3)COC4=C(C=CC=C4)Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.