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SLC6A19-IN-3

SLC6A19 Inhibitor

SLC6A19-IN-3 is a selective inhibitor of the SLC6A19 transporter, exhibiting an IC50 of 28 nM. This compound effectively blocks the transmembrane transport of phenylalanine, thereby decreasing its intestinal absorption and renal tubular reabsorption. SLC6A19-IN-3 is valuable in research related to metabolic disorders, particularly phenylketonuria, by facilitating insights into phenylalanine metabolism and its implications for treatment strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3104477-57-5
Applications	SLC6A19 Inhibitor
Formula	C₂₁H₂₅ClN₄O₂
Molecular Weight	400.90
SMILES	CNC(N1C[C@@H](C[C@H]2C[C@H]21)N(C3CC3)C(NCC#CC4=CC=CC(Cl)=C4)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.