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SLV-317 free base

Neurokinin-1 Receptor Antagonist

SLV-317 free base is a potent antagonist of the neurokinin-1 receptor, demonstrating oral bioactivity. It effectively inhibits substance P-induced effects, making it valuable for research into neurogenic inflammation and pain pathways. This compound is suitable for studies focused on the modulation of neurokinin signaling and its implications in various neurological disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	393101-98-9
Applications	Neurokinin-1 Receptor Antagonist
Formula	C₃₀H₃₁F₆N₇O₂
Molecular Weight	635.60
SMILES	O=C(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N2[C@H](CC3=CNC4=C3C=CC=C4)CN(CC5=NNN=C5CN6CCOCC6)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.