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SLV-317

Neurokinin-1 Receptor Antagonist

SLV-317 is a selective antagonist of the neurokinin-1 receptor, exhibiting oral bioavailability. It effectively inhibits substance P-induced responses, making it a valuable compound for studying neurokinin signaling pathways. This compound is particularly relevant in research focused on pain, anxiety, and other neurogenic conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	393183-40-9
Applications	Neurokinin-1 Receptor Antagonist
Formula	C₃₀H₃₃Cl₂F₆N₇O₂
Molecular Weight	708.53
SMILES	O=C(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N2[C@H](CC3=CNC4=C3C=CC=C4)CN(CC5=NNN=C5CN6CCOCC6)CC2.Cl.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.